Author:
de Lange W. E.,Snoep M. C.,Doorenbos H.
Abstract
ABSTRACT
Eight boys with severely delayed puberty without pathological cause were treated for 6 months with testosterone. This resulted in acceleration of skeletal maturation and a marked increase in height and weight. No adverse effects were found on hypothalamic-pituitary and gonadal maturation. Basal LH, FSH and testosterone levels rose to nearly adult values at follow-up within a year and pituitary responsiveness to LH-RH increased markedly.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
13 articles.
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