Author:
Blaquier Jorge,Forchielli Enrico,Dorfman Ralph I.
Abstract
ABSTRACT
Radioactive dehydroepiandrosterone, testosterone, androstenedione, 5-androstene-3β,17β-diol, and 4-androstene-3β,17β-diol have been incubated with whole blood obtained from normal males and females and from subjects with idiopathic hirsutism. The results show that transformations and interconversions of androgens can take place in whole blood and of particular interest is the transformation of the less to the more biologically active androgens. The implications of these transformations and interconversions in the possible role of blood in the control of endocrine homoeostasis is discussed.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
38 articles.
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