Author:
Axelrod Leonard R.,Kraemer Duane C.,Burdett James,Goldzieher Joseph W.
Abstract
ABSTRACT
The conversion of androstenedione and cortisol to 11β-hydroxyandrostenedione was studied by in vitro incubations of human and baboon adrenals and by in vivo perfusion of baboon adrenals. By both approaches, androstenedione appeared to be the major precursor. Some sidechain cleavage of cortisol also occurs during incubation with whole blood.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
30 articles.
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