BIREFRINGENT CRYSTALS IN HUMAN THYROID

Abstract

ABSTRACT A histological examination of 500 thyroid glands from unselected autopsies confirmed the earlier observation of Günther and Richter that anisotrophic crystals are commonly found in the thyroid gland. They may be found at all ages and in both sexes. They may be found in premature infants as early as colloid appears in the follicle. These crystals are most abundant in the elderly. They tend to disappear in thyroid glands badly damaged by disease. They have been identified as calcium oxylate monohydrate. Similar crystals are not seen in any other organ in the body. Their presence is an enigma.