EFFECTS OF 17α-HYDROXY-6α-METHYLPROGESTERONE ACETATE (DEPO-PROVERA) ON URINARY GONADOTROPHINS AND OESTROGENS IN MAN

Author:

Laron Z.,Rumney G.,Rat L.,Naji N.

Abstract

ABSTRACT Weekly injections of 17α-hydroxy-6α-methylprogesterone acetate to three patients with gonadal dysgenesis exhibiting high urinary gonadotrophins and one girl with marked enlargement of breasts and high urinary oestrogens, led to suppression of both urinary gonadotrophins and oestrogens in two patients and of oestrogens alone in the third case. There was no significant effect on the urinary 17-ketosteroids or 17-hydroxycorticosteroids.

Publisher

Bioscientifica

Subject

Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism

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