Gut-thyroid axis and celiac disease

Author:

Lerner Aaron12,Jeremias Patricia2,Matthias Torsten2

Affiliation:

1. 1B. Rappaport School of MedicineTechnion-Israel Institute of Technology, Haifa, Israel

2. 2AESKU.KIPP InstituteWendelsheim, Germany

Abstract

Autoimmune thyroiditis has an increased prevalence in patients with celiac disease and vice versa. The objective of the current review is to highlight the epidemiological, clinical, serological, pathological, pathophysiological, hormonal, genetic and immunological factors shared between the two entities. They might represent the two ends of the gut-thyroid axis where the cross-talks’ pathways are still unravelled. New observations are reviewed, highlighting some gut-thyroid interrelated pathways that potentially might lead to new therapeutic strategies.

Publisher

Bioscientifica

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

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