1. 1Department of Paediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
2. 2Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
3. 3Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Newcastle upon Tyne, UK
4. 4Department of Child Health, University of Glasgow School of Medicine, Glasgow, UK
5. 5Department of Paediatrics, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK
6. 6Wellcome Trust-MRC Institute of Metabolic Sciences, University of Cambridge, Cambridge, UK
7. 7Newcastle Clinical Trials Unit, Statistics & Physics, Newcastle University, Newcastle-upon-Tyne, UK
8. 8School of Mathematics, Statistics & Physics, Newcastle University, Newcastle-upon-Tyne, UK
9. 9Department of Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK