Acquired Sideroblastic Anemia: An exploratory Comparative Statistical Analysis Between Clonal and Non-clonal cases
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Published:2022-08-27
Issue:1
Volume:14
Page:e2022067
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ISSN:2035-3006
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Container-title:Mediterranean Journal of Hematology and Infectious Diseases
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language:
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Short-container-title:Mediterr J Hematol Infect Dis
Author:
Soliman Dina Sameh,Kohla Samah,Fareed Shehab,Akiki Susanna,Amer Aliaa,Ganwo Ibrahim,Chandra Prem,El-Omri Halima,Ibrahim Feryal
Abstract
Sideroblastic anemia (SA) is a rare heterogenous group of inherited and acquired bone marrow disorders. We retrospectively studied the clinicopathologic characteristics, cytogenetic findings, and disease outcome of patients with acquired sideroblastic anemia (ASA) and performed a comparative analysis between clonal and non-clonal cases. 15 patients of ASA were detected: clonal SA (10 cases, 66.7%) including MDS, MDS/MPN, AML and t-MNs with ring sideroblasts) and SA secondary to non-clonal causes (5 cases; 33.3%), including copper deficiency (2 sideroblastic anemia, copper deficiency, non-clonal sideroblastic anemia cases), pyridoxine deficiency diagnosed during pregnancy, and 2 patients with idiopathic SA.Key
Keywords: sideroblastic anemia, copper deficiency, non-clonal sideroblastic anemia
Publisher
Hematology Section, Dept. of Radiological Science and Hematology, Catholic University, Rome, Italy
Subject
Infectious Diseases,Hematology