Scalable manufacture of a disposable, storage-stable eight-channel microfluidic device for rapid testing of platelet, coagulation, and drug function under whole blood flow
Author:
Affiliation:
1. Department of Chemical and Biomolecular Engineering, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Funder
National Institutes of Health
Publisher
AIP Publishing
Subject
Condensed Matter Physics,General Materials Science,Fluid Flow and Transfer Processes,Colloid and Surface Chemistry,Biomedical Engineering
Link
http://aip.scitation.org/doi/pdf/10.1063/5.0023312
Reference43 articles.
1. P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions
2. Microfluidic Assay of Platelet Deposition on Collagen by Perfusion of Whole Blood from Healthy Individuals Taking Aspirin
3. FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow
4. Side view thrombosis microfluidic device with controllable wall shear rate and transthrombus pressure gradient
5. Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces Under Flow
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