AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage

Author:

Li Juan1,Wen Amy M.1ORCID,Potla Ratnakar12,Benshirim Ezekiel13,Seebarran Ariel14,Benz Maximilian A.1ORCID,Henry Olivier Y. F.1,Matthews Benjamin D.25,Prantil-Baun Rachelle1,Gilpin Sarah E.1,Levy Oren1,Ingber Donald E.126ORCID

Affiliation:

1. Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA

2. Vascular Biology Program, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA

3. Department of Integrative Biology, Harvard College, Cambridge, Massachusetts 02138, USA

4. Department of Materials Science and Engineering, University of Toronto, Toronto, Ontario M5S 3E4, Canada

5. Department of Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA

6. Harvard School of Engineering and Applied Sciences, Cambridge, Massachusetts 02139, USA

Funder

National Heart, Lung, and Blood Institute

National Institute of Biomedical Imaging and Bioengineering

Wyss Institute for Biologically Inspired Engineering at Harvard University

Publisher

AIP Publishing

Subject

Biomedical Engineering,Biomaterials,Biophysics,Bioengineering

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