1. Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada
2. Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada
3. Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada
4. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada
5. Department of Physics and Astronomy, University of Denver, Colorado, Colorado 80208, USA
6. Molecular and Cellular Biophysics, University of Denver, Colorado, Colorado 80208, USA