Miniaturized microsphere-assisted microscopy

Author:

Perrin Stephane1ORCID,Pierron Robin1ORCID,Gerard Philippe12ORCID,Montgomery Paul1ORCID,Lecler Sylvain12ORCID

Affiliation:

1. ICube Research Institute, University of Strasbourg – CNRS 1 , 300 Boulevard Sébastien Brant, 67412 Illkirch, France

2. INSA Strasbourg 2 , 24 Boulevard de la Victoire, Strasbourg, France

Abstract

Microsphere-assisted microscopy is a sub-diffraction-limited imaging technique, which uses dielectric microspheres to collect the near-field information of an object. In this work, the bulk of the classical microsphere-based system is reduced by the simple introduction of a ball lens. The miniaturized imaging system has been designed and vertically assembled. Performance of the proposed dual-sphere system is quantified through numerical simulations and experiments. A theoretical impulse response with a full width at half maximum smaller than half of the wavelength is reached in air. As a proof of concept, 500-nm-period standard gratings and gold nanoparticles are observed without a classical objective, validating a sub-wavelength resolution with a high imaging quality and low aberrations over the field of view.

Funder

SATT Conectus Alsace

FRCR - Grand Est

Publisher

AIP Publishing

Subject

Physics and Astronomy (miscellaneous)

Reference38 articles.

1. Optical stethoscopy: Image recording with resolution λ/20;Appl. Phys. Lett.,1984

2. Far-field optical nanoscopy;Science,2007

3. Imaging intracellular fluorescent proteins at nanometer resolution;Science,2006

4. See https://www.nobelprize.org/prizes/chemistry/2014/summary/ for NobelPrize.org, “ The Nobel Prize in Chemistry 2014,” (2018) (accessed 11 April 2023).

5. Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy;J. Microsc.,2000

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3