Structural biology and public health response to biomedical threats

Author:

Lenkiewicz Joanna1ORCID,Bijak Vanessa1ORCID,Poonuganti Shrisha1ORCID,Szczygiel Michal12ORCID,Gucwa Michal12ORCID,Murzyn Krzysztof2ORCID,Minor Wladek1ORCID

Affiliation:

1. Department of Molecular Physiology and Biological Physics, University of Virginia 1 , Charlottesville 22908, USA

2. Department of Computational Biophysics and Bioinformatics, Jagiellonian University 2 , Krakow, Poland

Abstract

Over the course of the pandemic caused by SARS-CoV-2, structural biologists have worked hand in hand with groups developing vaccines and treatments. However, relying solely on in vitro and clinical studies may be insufficient to guide vaccination and treatment developments, and other healthcare policies during virus mutations or peaks in infections and fatalities. Therefore, it is crucial to track statistical data related to the number of infections, deaths, and vaccinations in specific regions and present it in an easy-to-understand way.

Funder

National Institute of General Medical Sciences

Yes, funding has been received from NIH

Publisher

AIP Publishing

Subject

Spectroscopy,Condensed Matter Physics,Instrumentation,Radiation

Reference58 articles.

1. See https://www.who.int/health-topics/middle-east-respiratory-syndrome-coronavirus-mers for “information about MERS coronavirus.”

2. Structural basis for catalysis and ubiquitin recognition by theSevere acute respiratory syndrome coronaviruspapain-like protease

3. See https://www.worldometers.info/coronavirus/ for “the number of infections and deaths caused by COVID-19 worldwide.”

4. The Protein Data Bank

5. The tangled history of mRNA vaccines

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