A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices

Author:

Mousavi Shaegh Seyed Ali12,De Ferrari Fabio123ORCID,Zhang Yu Shrike124,Nabavinia Mahboubeh125,Binth Mohammad Niema126,Ryan John127,Pourmand Adel128,Laukaitis Eleanor129ORCID,Banan Sadeghian Ramin1210,Nadhman Akhtar1211,Shin Su Ryon12,Nezhad Amir Sanati1212,Khademhosseini Ali1241013,Dokmeci Mehmet Remzi124

Affiliation:

1. Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02139, USA

2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA

3. Department of Electronics and Telecommunications, Politecnico di Torino, 10129 Torino, Italy

4. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts 02139, USA

5. Department of Chemical Engineering, Sahand University of Technology, 5331711111 Tabriz, Iran

6. Faculty of Applied Science and Engineering, University of Toronto, Toronto, Ontario M5S 3E3, Canada

7. Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA

8. Department of Electrical Engineering, Sahand University of Technology, 5331711111 Tabriz, Iran

9. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA

10. WPI-Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan

11. Sulaiman Aba Al Khail Centre for Interdisciplinary Research in Basic Sciences (SA-CIRBS), International Islamic University, Islamabad, Pakistan

12. BioMEMS and Bioinspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta T2N 1N4, Canada

13. Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia

Funder

National Institute of Allergy and Infectious Diseases (NIAID)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

National Institute of Dental and Craniofacial Research (NIDCR)

Defense Threat Reduction Agency (DTRA)

National Heart, Lung, and Blood Institute (NHLBI)

Publisher

AIP Publishing

Subject

Condensed Matter Physics,General Materials Science,Fluid Flow and Transfer Processes,Colloid and Surface Chemistry,Biomedical Engineering

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