Photodynamic therapy in the treatment of intraepithelial neoplasia of the cervix, vulva and vagina-Reference-Cited by-同舟云学术

Photodynamic therapy in the treatment of intraepithelial neoplasia of the cervix, vulva and vagina

Published:2021-02-04 Issue:4 Volume:9 Page:31-39
ISSN:2413-9432
Container-title:Biomedical Photonics
language:
Short-container-title:Biomedical photonics

Author:

Filonenko E. V.¹,Trushina O. I.¹,Novikova E. G.¹,Zarochentseva N. V.²,Rovinskaya O. V.²,Ivanova-Radkevich V. I.³,Kaprin A. D.⁴

Affiliation:

1. P.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian Federation

2. Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health of the Moscow Region

3. Peoples’ Friendship University of Russia (RUDN University)

4. P.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian Federation; Peoples’ Friendship University of Russia (RUDN University)

Abstract

In the present review the authors analyzed the effectiveness of treatment of intraepithelial neoplasia I-II-III of the cervix (CIN), vulva (VIN) and vagina (VaIN) using photodynamic therapy (PDT). PDT is a method based on exposure to light after preliminary introduction of a photosensitizer into the body with the formation of singlet oxygen, which has a cytotoxic effect. The results of research on the use of PDT with various photosensitizers in the complex of therapeutic measures in patients with CIN, VIN, VaIN are presented. These data on the effectiveness and safety of PDT, ease of use allow this medical technology to be attributed to one of the most promising areas in the treatment of pathological intraepithelial changes of the cervix, vulva and vagina. The presented information allows focusing the attention on the PDT method and informing doctors and researchers about the broad prospects for applying this treatment method in clinical practice.

Publisher

Russian Photodynamic Association

Subject

Dermatology,Surgery

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