Affiliation:
1. From the Institute for Physical Chemistry of the University of Upsala, Sweden, the Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York
Abstract
1. The sedimentation constant of hog thyroglobulin is 19.2ċ10–13. That of human thyroglobulin is essentially the same.
2. The specific volume of hog thyroglobulin is 0.72.
3. The isoelectric point of native hog thyroglobulin is at pH 4.58, that of denatured thyroglobulin at pH 5.0.
4. The molecular weight of hog thyroglobulin is, in round numbers, 700,000, as calculated from the sedimentation and diffusion constants, or 650,000, as calculated from the sedimentation equilibrium data.
5. The thyroglobulin molecule deviates markedly from the spherical.
Publisher
Rockefeller University Press
Cited by
129 articles.
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