Affiliation:
1. From the Department of Genetics, Carnegie Institution of Washington, Cold Spring Harbor, Long Island
Abstract
In experiments of 6 hours duration, no replacement of phosphorus or purine and pyrimidine carbon in DNA, nor flow of these atoms from RNA to DNA, could be detected in rapidly growing cultures of E. coli. The slow replacement that has been demonstrated for many substances in non-proliferating tissues of other organisms, though it may occur also in bacteria, is not greatly accelerated under conditions of rapid cellular growth, and therefore cannot be a characteristic feature of synthetic processes.
Publisher
Rockefeller University Press
Cited by
94 articles.
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1. Phosphorus-32 in the Phage Group: radioisotopes as historical tracers of molecular biology;Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences;2009-03
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3. Über die Wirkung von Urethan und N-Lost auf den Nukleinsäure- und Protein-Stoffwechsel von E. coli;Zeitschrift für allgemeine Mikrobiologie;2007-01-24
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