Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
Author:
Affiliation:
1. School of Kinesiology and Health Sciences, York University 1 , Toronto, ON, Canada
2. Women’s and Children’s Health, Karolinska Institute 2 , Stockholm, Sweden
3. Physiology and Pharmacology, Karolinska Institute 3 , Stockholm, Sweden
Abstract
Funder
Swedish Research Council
Publisher
Rockefeller University Press
Subject
Physiology
Link
https://rupress.org/jgp/article-pdf/doi/10.1085/jgp.202213224/1446259/jgp_202213224.pdf
Reference15 articles.
1. A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions;Azimi;ACS Pharmacol. Transl. Sci.,2020
2. Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle;Bellinger;Nat. Med.,2009
3. STIM- and Orai-mediated calcium entry controls NF-κB activity and function in lymphocytes;Berry;Cell Calcium,2018
4. The TREAT-NMD DMD global database: Analysis of more than 7,000 Duchenne muscular dystrophy mutations;Bladen;Hum. Mutat.,2015
5. Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle;Edwards;Am. J. Physiol. Cell Physiol.,2010
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