Dynamic Characteristics of Retinal Ganglion Cell Responses in Goldfish

Abstract

A cross-correlation technique has been applied to quantify the dependence of the dynamic characteristics of retinal ganglion cell responses in goldfish on intensity, wavelength, spatial configuration, and spot size. Both theoretical and experimental evidence justify the use of the cross-correlation procedure which allows the completion of rather extensive measurements in a relatively short time. The findings indicate the following. (a) The shape of the amplitude characteristics depends on the energy per unit of time (power) falling within the center of a receptive field rather than on the intensity of the stimulus spot. For spot diameters of up to 1 mm, identical amplitude characteristics can be obtained by interchanging area and intensity. Therefore the receptor processes do not contribute to the change in the amplitude characteristics as a function of the power of the stimulus light. (b) For high frequencies the amplitude characteristics obtained as a function of power join together in a common envelope if plotted on an absolute sensitivity scale. For spontaneous ganglion cells this envelope holds over a range of three log units and the shape is identical for central and peripheral processes. (c) The amplitude characteristics of the central and peripheral processes converging to a ganglion cell are identical, irrespective of the sign (on or off) and the spectral coding of the response. Therefore we have no evidence for interneurons in the goldfish retina unique to the periphery of the receptive field.