Activation of excitatory glycine NMDA receptors: At the mercy of a whimsical GluN1 subunit-Reference-Cited by-同舟云学术

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Activation of excitatory glycine NMDA receptors: At the mercy of a whimsical GluN1 subunit

Published:2023-05-03 Issue:6 Volume:155 Page:
ISSN:0022-1295
Container-title:Journal of General Physiology
language:en
Short-container-title:

Author:

He Miaomiao¹²³^ORCID,Wollmuth Lonnie P.²⁴³^ORCID

Affiliation:

1. Graduate Program in Biochemistry and Structural Biology Stony Brook University 1 , Stony Brook, NY, USA

2. Center for Nervous System Disorders, Stony Brook University 2 , Stony Brook, NY, USA

3. Stony Brook University 4 Department of Biochemistry and Cell Biology, , Stony Brook, NY, USA

4. Stony Brook University 3 Department of Neurobiology and Behavior, , Stony Brook, NY, USA

Abstract

Glycine-gated NMDA receptors contribute to brain functions and disorders. Rouzbeh et al. shed light on their odd pharmacology.

Funder

National Institutes of Health

Stony Brook University-Brookhaven National Labs

Publisher

Rockefeller University Press

Subject

Physiology

Link

https://rupress.org/jgp/article-pdf/doi/10.1085/jgp.202313391/1452020/jgp_202313391.pdf

Reference18 articles.

1. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors;Awobuluyi;Mol. Pharmacol.,2007

2. GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits;Bossi;Neuron,2022

3. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits;Chatterton;Nature,2002

4. GluN3A NMDA receptor subunits: More enigmatic than ever?;Crawley;J. Physiol.,2022

5. Protons potentiate GluN1/GluN3A currents by attenuating their desensitisation;Cummings;Sci. Rep.,2016

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