Tweaking the catalytic efficiency of the CFTR ion channel
Author:
Affiliation:
1. Emory University School of Medicine 1 , Atlanta, GA, USA
Abstract
Publisher
Rockefeller University Press
Subject
Physiology
Link
https://rupress.org/jgp/article-pdf/doi/10.1085/jgp.202313343/1450379/jgp_202313343.pdf
Reference20 articles.
1. An ancient CFTR ortholog informs molecular evolution in ABC transporters;Cui;Dev. Cell,2019
2. Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR;Cui;J. Gen. Physiol.,2014
3. Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients;Dean;Cell,1990
4. Learning the ABCs one at a time: Structure and mechanism of ABC transporters;Ford;Biochem. Soc. Trans.,2019
5. The block of CFTR by scorpion venom is state-dependent;Fuller;Biophys. J.,2005
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