A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART-Reference-Cited by-同舟云学术

A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART

Published:1922-05-20 Issue:5 Volume:4 Page:559-568
ISSN:1540-7748
Container-title:Journal of General Physiology
language:en
Short-container-title:

Author:

Carlson A. J.¹

Affiliation:

1. From the Marine Biological Laboratory, Leland Stanford Junior University, Stanford University, the Marine Biological Laboratory, University of California, La Jolla, and the Marine Biological Laboratory, Woods Hole.

Abstract

1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They paralyze or block the cardioinhibitory nerves, but not the cardioaccelerator nerves. 4. In the Limulus heart these drugs act primarily on the heart ganglion, not on the heart muscle or the intrinsic motor nerve fibers.

Publisher

Rockefeller University Press

Subject

Physiology

Link

http://rupress.org/jgp/article-pdf/4/5/559/1241309/559.pdf

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