Clinical challenges with calcitonin-negative medullary thyroid carcinoma: three case reports and a review of the literature-Reference-Cited by-同舟云学术

Clinical challenges with calcitonin-negative medullary thyroid carcinoma: three case reports and a review of the literature

Published:2022-03 Issue:3 Volume:104 Page:221-230
ISSN:0035-8843
Container-title:The Annals of The Royal College of Surgeons of England
language:en
Short-container-title:annals

Author:

Jingzhu Z¹²,Xiangqian Z¹²,Ming G¹²,Yi P¹²,Jiadong C¹²,Xinwei Y¹²,Guangwei Xu¹²

Affiliation:

1. Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, P. R. China

2. Tianjin’s Clinical Research Centre for Cancer, P. R. China

Abstract

Medullary thyroid carcinoma (MTC) is relatively rare, and has the main feature of calcitonin (Ct) secretion. However, a few cases of MTC with negative serum calcitonin have been reported in the literature, so the diagnosis and follow up of Ct-negative MTCs are still a challenge. Here we present three cases of Ct-negative MTCs, illustrating the rarity of the disease and challenges in managing it, together with a review of the literature of 39 MTCs with negative serum Ct.

Publisher

Royal College of Surgeons of England

Subject

General Medicine,Surgery

Link

https://publishing.rcseng.ac.uk/doi/pdf/10.1308/rcsann.2020.7118

Reference21 articles.

1. Medullary, Anaplastic, and Metastatic Cancers of the Thyroid

2. Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma

3. Thyroid Cancer Incidence Patterns in Sao Paulo, Brazil, and the U.S. SEER Program, 1997–2008

4. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer

5. Medullary Thyroid Cancer: Management Guidelines of the American Thyroid Association

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer;Journal of Clinical Practice;2023-10-19

2. Medullary thyroid carcinoma;Expert Review of Anticancer Therapy;2023-08-30

3. Oncologic outcomes of calcitonin-negative medullary thyroid carcinoma;Frontiers in Endocrinology;2022-11-23