From acute pulmonary embolism to post-pulmonary embolism sequelae

Author:

Farmakis Ioannis T.12ORCID,Keller Karsten134,Barco Stefano15,Konstantinides Stavros V.16,Hobohm Lukas13ORCID

Affiliation:

1. Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany

2. Cardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece

3. Center for Cardiology, Cardiology I, University Medical Center Mainz, Germany

4. Department of Sports Medicine, Internal Medicine VII, Medical Clinic, University Hospital Heidelberg, Germany

5. Department of Angiology, University Hospital Zurich, Switzerland

6. Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece

Abstract

Summary: Aim of this narrative review is to summarize the functional and hemodynamic implications of acute PE and PE sequelae, namely the post-PE syndrome. Briefly, we will first describe the epidemiology, diagnostic procedures, and therapeutic approaches of acute PE. Then, we will provide a definition of the post-PE syndrome and present the so far accumulated evidence regarding its epidemiology and the implications that arise for further diagnosis and treatment. Lastly, we will explore the most devastating long-term complication of PE, namely chronic thromboembolic pulmonary hypertension (CTEPH), and recent advances in its management.

Publisher

Hogrefe Publishing Group

Subject

Cardiology and Cardiovascular Medicine

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