Analysis of the association of the polymorphic locus rs3218536 of the xrcc2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortosta-Reference-Cited by-同舟云学术

Analysis of the association of the polymorphic locus rs3218536 of the xrcc2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortosta

Published:2024-04-24 Issue:1 Volume:10 Page:36-39
ISSN:2500-2937
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Author:

Mingazheva Elvira Tagirovna¹,Valova Yana Valerievna²,Prokofieva Daria Simonovna¹,Andreeva Ekaterina Anatolevna¹,Faishkhanova Rania Razyapovna³,Khusnutdinova Elza Kamilevna⁴

Affiliation:

1. Ufa University of Science and Technology

2. Ufa University of Science and Technology; Ufa scientific research institute of occupational medicine and human ecology

3. Republican Clinical Oncology Dispensary of the Ministry of Health of the Republic of Bashkortostan

4. Ufa University of Science and Technology;The institute of biochemistry and genetics of the Ufa federal research center of the R ussian academy of sciences

Abstract

Ovarian cancer is the most aggressive form of all malignant neoplasms of the female reproductive system. Despite certain advances achieved in the diagnosis and treatment of this disease, survival rates are still unsatisfactory, which dictates the need for further study of the etiological factors and pathogenetic mechanisms underlying ovarian carcinogenesis. The purpose of the work was to conduct an association analysis of the rs3218536 polymorphic variant of the XRCC2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortostan. As a result of the study, it was not possible to detect an association of the studied polymorphic locus with the risk of developing ovarian cancer in women from the Republic of Bashkortostan

Publisher

LLC MedTestInfo

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