Affiliation:
1. 1International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
Abstract
The plant kingdom offers a rich source of structural biodiversity in the form of a variety of natural products. Our work on new bioactive compounds from medicinal plants has led to the isolation and structure elucidation of a number of exciting new pharmacophores. Bioassay-guided fractionation has recently led to the discovery of a series of new acetylcholinesterase, urease and a-glucosidase inhibitors, antioxidants and other classes of bioactive compounds, which will be presented. A theory based on hydrogen bonding on the chemical basis of memory storage in the brain is presented.
Subject
General Chemical Engineering,General Chemistry
Cited by
116 articles.
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1. Polarity directed solvent extracts from Bukiniczia Cabulica (Boiss.) Lincz. ameliorate scopolamine induced amnesia: HPLC-DAD polyphenolics analysis, cholinesterase, COX2, BACE1 inhibitory, anti-amyloid, antioxidant, molecular docking and behavioral correlates;Journal of Molecular Liquids;2024-02
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