New methods for high-throughput synthesis-Reference-Cited by-同舟云学术

New methods for high-throughput synthesis

Published:2001-07-01 Issue:7 Volume:73 Page:1103-1111
ISSN:1365-3075
Container-title:Pure and Applied Chemistry
language:
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Author:

Kobayashi Shū¹,Akiyama Ryo¹

Affiliation:

1. 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Abstract

New methodologies for library synthesis have been developed. They are based on new carboncarbon bond-formation reactions in the solid-phase and organic synthesis using polymer-supported catalysts. We have immobilized alkyl glyoxylate equivalents onto resins and prepared novel polymer-supported imines. We have also developed unprecedented polymer-supported catalysts such as microencapsulated scandium trifluoromethanesulfonate [MC Sc(OTf)3], osmium tetroxide (MC OsO4), and palladium triphenylphosphine [MC Pd(PPh3)] for high-throughput synthesis.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

Link

https://www.degruyter.com/document/doi/10.1351/pac200173071103/pdf

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