Diels_Alder reactions in water

Author:

Otto Sijbren1,Engberts Jan B. F. N.1

Affiliation:

1. 1Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands

Abstract

This review illustrates how water, as an environmentally friendly solvent, can have significant additional benefits when it is used as a solvent for the Diels_Alder reaction. The mechanism by which the unique properties of water enhance the rate and selectivity are discussed. Also, possibilities for the achievement of further increases in rate and enantioselectivity of aqueous Diels_Alder reactions through Lewis-acid and micellar catalysis are reviewed.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

Reference3 articles.

1. on this topic is forthcoming Reactions and Synthesis in Pure and Surfactant Systems ) Marcel New to be published;Otto;review Applied Chemistry,1372

2. II;Sangwan;Chem Soc Trans Am Chem Soc Org Chem,1989

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