Chemomechanics with molecular force probes

Author:

Huang Zhen1,Boulatov Roman1

Affiliation:

1. 1Department of Chemistry, University of Illinois, Urbana, IL 61801, USA

Abstract

Chemomechanics is an emerging area at the interface of chemistry, materials science, physics, and biology that aims at quantitative understanding of reaction dynamics in multiscale phenomena. These are characterized by correlated directional motion at multiple length scales—from molecular to macroscopic. Examples include reactions in stressed materials, in shear flows, and at propagating interfaces, the operation of motor proteins, ion pumps, and actuating polymers, and mechanosensing. To explain the up to 1015-fold variations in reaction rates in multiscale phenomena—which are incompatible within the standard models of chemical kinetics—chemomechanics relies on the concept of molecular restoring force. Molecular force probes are inert molecules that allow incremental variations in restoring forces of diverse reactive moieties over hundreds of piconewtons (pN). Extending beyond the classical studies of reactions of strained molecules, molecular force probes enable experimental explorations of how reaction rates and restoring forces are related. In this review, we will describe the utility of one such probe—stiff stilbene. Various reactive moieties were incorporated in inert linkers that constrained stiff stilbene to highly strained macrocycles. Such series provided the first direct experimental validation of the most popular chemomechanical model, demonstrated its predictive capabilities, and illustrated the diversity of relationships between reaction rates and forces.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

Reference50 articles.

1. Organic Mechanochemistry and its Practical Applications;Todres,2006

2. nchem;Piermattei;Nat Chem,2009

3. de;Pablo;MRS Bull,2007

Cited by 43 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3