Prevalence of multidrug resistance pathogens in dermatology: A retrospective study in Romania, 2018-2022

Abstract

Antimicrobial resistance (AMR) is now a major challenge to clinicians in treating patients. The purpose of our study was to determine the incidence of multidrug resistant (MDR) strains and antibiotic resistance profile in department of dermatology-venereology from a Romanian infectious disease’s hospital. We analyzed 1,152 bacterial strains, we obtained 34.5% MDR strains, identifying the following species:<i> staphylococcus aureus</i> 43.6%, <i>enterococcus </i>spp 16.7%, <i>escherichia coli</i><i> </i>31.0%, <i>proteus </i>spp 27.1%, <i>klebsiella</i> spp. 22.4%, <i>pseudomonas</i> spp. 34.8%. Overall, the rate of methicillin-resistant <i>staphylococcus aureus</i> was 76.1%; extended spectrum beta-lactamase production was 46.1% for <i>escherichia coli</i> and 66.0% for <i>klebsiella pneumoniae</i>; carbapenems-resistance was 51.0% for <i>pseudomonas aeruginosa</i>. All strains of <i>E. coli</i> and <i>klebsiella</i> were sensitive to meropenem. Our results confirm the high level of AMR, and continuous monitoring is essential for updating the local diagnostic and treatment protocols for dermatological infections.