Pregabalin and gabapentin abuse among university students in Jordan: A cross sectional study

Author:

Altarifi Ahmad A1ORCID,Obeidat Omar2ORCID,Guzu Ahmad2ORCID,Said Amr2ORCID,Albakheet Mahmoud2ORCID,Makkawi Ahmad2ORCID,Hasan Zuheir3ORCID,Azab Mohammed4ORCID,Alotaibi Moureq R5ORCID,Kheirallah Khalid6ORCID,Saleh Tareq2ORCID

Affiliation:

1. Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, JORDAN

2. Department of Pharmacology and Public Health, Faculty of Medicine, The Hashemite University, Zarqa, JORDAN

3. Department of Anatomy, Physiology, and Biochemistry, Faculty of Medicine, The Hashemite University, Zarqa, JORDAN

4. Department of Microbiology, Pathology, and Forensic Medicine, Faculty of Medicine, The Hashemite University, Zarqa, JORDAN

5. Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, SAUDI ARABIA

6. Department of Public Health, Faculty of Medicine, Jordan University of Science and Technology, Irbid, JORDAN

Abstract

<b>Introduction</b>: Pregabalin and gabapentin (or gabapentanoids) have been reported to be abused for potentially euphoric effects.<br /> <b>Objectives</b>: In this work, we conducted a descriptive, cross-sectional study among university students from Jordan utilizing a structured online questionnaire.<br /> <b>Results</b>: 96.1% of the participants indicated no previous or current use of gabapentanoids, while 53 (3.9%) self-reported previous or current use (ever-use) of any of both drugs. The rate of abuse was higher among males and older students’ groups. 50.9% of drug users did not obtain a valid prescription. Most abusers indicated that their use of both drugs was for non-medical reasons (39.6%), and 69.8% students used both drugs despite being aware of their adverse effects. Hypersomnia was the most reported adverse effect. However, most participants (64.2%) did not report any withdrawal symptoms upon drug discontinuation. Marijuana/hashish was the most consumed substance with gabapentanoids.<br /> <b>Conclusions</b>: Our results invite for further prescribed drug control and increasing the awareness against drug abuse among the youth in Jordan.

Publisher

Modestum Ltd

Subject

General Medicine

Reference32 articles.

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