Affiliation:
1. Perm State Medical University named after Academician E.A. Wagner
Abstract
Aim – to study the dynamics of ovarian parameters in women from the first period of adulthood to early old age measured by sonography.
Material and methods. The study used the results of an ultrasound examination of 81 women with normal pelvic dimensions, without reproductive organ pathology, having maximum two pregnancies in life history more than one year before the study. All participants gave their consent to routine examination. The procedure consisted of measuring the length, width, anteroposterior size and volume of the ovaries by transvaginal access according to standard protocols. The subjects were divided into three groups according to anatomical age classification. The first group consisted of 29 early adulthood women (22 to 35 years); the second group included 23 women in middle adulthood (36 to 56 years) and 29 early old age women (57 to 73 years).
Results. All the ovarian parameters decreased by early old age (p 0.01). At the same time, a trend towards macroanatomic asymmetry of the ovaries with larger dimensions in the right side was revealed in each of the studied age periods (p 0.05).
Conclusion. The results of a lifetime comparative analysis of the anatomical dimensions of the ovaries in women contribute to the knowledge of their age-specific structure and requires a future detailed study. A new knowledge is required to develop modern methods for preventing pathologies of the female reproductive system and to provide timely, high-quality medical care.
Publisher
FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation
Reference23 articles.
1. Li Shu-Yun, Bhandary B, Gu X, De Falco T. Perivascular cells support folliculogenesis in the developing ovary. Proc Natl Acad Sci USA. 2022;119(41):e2213026119. https://doi.org/10.1073/pnas.2213026119
2. Nicol B, Estermann MA, Humphrey H-C Yao, Mellouk N. Becoming female: Ovarian differentiation from an evolutionary perspective. Front Cell Dev Biol. 2022;10:944776. https://doi.org/10.3389/fcell.2022.944776
3. Zhang Z, Huang L, Brayboy L. Macrophages: an indispensable piece of ovarian health. Biol Reprod. 2021;104(3):527-538. https://doi.org/10.1093/biolre/ioaa219
4. Gasparyan SA, Vasilenko IA, Papikova KA, Drosova LD. Menopause: up the stairs leading down. Medical Council. 2020;(13):76-83. (In Russ.). [Гаспарян С.А., Василенко И.А., Папикова К.А., Дросова Л.Д. Менопауза: вверх по лестнице, ведущей вниз. Медицинский совет. 2020;(13):76-83]. https://doi.org/0.21518/2079-701X-2020-13-76-83
5. Kotova OV, Akarachkova ES, Belyaev AA. Psychosomatic health problems in menopausal women. Clinical analysis in obsterics, gyneology and reproductology. 2021;1(3):28-32. (In Russ.). [Котова О.В., Акарачкова Е.С., Беляев А.А. Проблемы психосоматического здоровья у женщин в период менопаузы. Клинический разбор в акушерстве, гинекологии и репродуктологии. 2021;1(3):28-32]. https://doi.org/10.47407/kragr2021.1.3.000021