Classification and clinical significance of Papillomavirus infection in domestic cats
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Published:2023-12-15
Issue:4
Volume:66
Page:53-62
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ISSN:1454-7406
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Container-title:Scientific Papers Journal VETERINARY SERIES
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language:
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Short-container-title:SPJVS
Author:
, Paul Țuțu, Oana Irina TanaseORCID, , Florentina DarabanORCID, , Mihaela Anca DascăluORCID, , Dumitru-Octavian Soreanu, , Mihai MareșORCID,
Abstract
During the last decades, the infection with papillomavirus in domestic cats gained interest from the veterinary community due to its significant impact on the companion's animal's health. Therefore, in this review, we aim to present a concise classification of feline papillomaviruses and their clinical relevance in domestic felines. Initially, the different types of papillomaviruses affecting domestic cats are described. Here, we emphasize the molecular diversity and transmission ways to better understand each virus type and its clinical implications. Furthermore, we explore the clinical importance of papillomavirus infections, analyzing their various manifestations such as skin or oral lesions. We outline the signs and symptoms of these infections, shedding light on the oncogenic mechanisms used by the virus. The knowledge gained from this analysis holds the potential to refine veterinary medical practices, enabling the effective management of this condition and ultimately enhancing the overall quality of life for our feline companions.
Publisher
Universitatea de Ştiinţele Vieţii "Ion Ionescu de la Brad" din Iaşi
Reference73 articles.
1. 1.Altamura, G., Cardeti, G., Cersini, A., Eleni, C., Cocumelli, C., Bartolomé del Pino, L. E., Razzuoli, E., Martano, M., Maiolino, P., & Borzacchiello, G. (2020). Detection of Felis catus papillomavirus type-2 DNA and viral gene expression suggest active infection in feline oral squamous cell carcinoma. Veterinary and Comparative Oncology, 18(4), 494-501. https://doi.org/10.1111/vco.12569 2. 2.Altamura, G., Corteggio, A., & Borzacchiello, G. (2016). Felis catus papillomavirus type 2 E6 oncogene enhances mitogen-activated protein kinases and Akt activation but not EGFR expression in an in vitro feline model of viral pathogenesis. Veterinary Microbiology, 195, 96- 100. https://doi.org/10.1016/J.VETMIC.2016.09.013 3. 3.Altamura, G., Corteggio, A., Pacini, L., Conte, A., Pierantoni, G. M., Tommasino, M., Accardi, R., & Borzacchiello, G. (2016). Transforming properties of Felis catus papillomavirus type 2 E6 and E7 putative oncogenes in vitro and their transcriptional activity in feline squamous cell carcinoma in vivo. Virology, 496, 1-8. https://doi.org/10.1016/J.VIROL.2016.05.017 4. 4.Altamura, G., Jebara, G., Cardeti, G., & Borzacchiello, G. (2018). Felis catus papillomavirus type-2 but not type-1 is detectable and transcriptionally active in the blood of healthy cats. Transboundary and Emerging Diseases, 65(2), 497-503. https://doi.org/10.1111/tbed.12732 5. 5.Bernard, H. U., Burk, R. D., Chen, Z., van Doorslaer, K., Hausen, H. zur, & de Villiers, E. M. (2010). Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Virology, 401(1), 70-79. https://doi.org/10.1016/j.virol.2010.02.002
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