Role of Helicobacter Pylori in Gastro-Intestinal Tract Disorders (Gitds) Among Patients in Kirkuk City, Iraq

Abstract

ABSTRACT: In recent works Helicobacter pylori (H. pylori) become a significant criteria and essential diagnostic tool for studying the etiology of gastro-intestinal tract disorders (GITDs), for this purpose a total of stool samples were collected from 266 patients from both gender ,they were aging from below one year to over than 70 years. Their compliance with epi-gastric pain, diarrhea weigh loose and other disorders. Types of GITDS were detected and classified by the gastro-enterologists in two main Hospitals and from patients attending Private clinics and medical labs in Kirkuk city. H. pylori was detected form stool samples by using rapid lateral immune-chromatography assay (RLICA). GITDs involve, H. pylori positive distributed in 132 (49.62%), followed by 74 (27.81 % ), 59(22.18 %), 7(2.63 %), 3(1.12%) and 2(0.75 %) for irritable bowel diseases, inflammatory bowel diseases, peptic ulcer, ulcerative colitis and duodenal ulcers diseases respectively. Whereas 171, (64.28%) were positive for parasitic infection, P<0.05 .Moreover other 48, (18.04 %) stool samples were non-identified it's about from the described diseases. A total of132 (49.62 %) of H. pylori positive samples were distributed in 46(38.84 %) samples for IBD versus to 41(31.81 %) for IBS and 33(25%) were positive for parasitic infections, p <0.05. According to age; highest rate 10 (55.55 %) of H. pylori was recorded among patients aging from 61 to 70 years, whom they have IBD. Whereas 7 (70 %) have IBS within age group from 41 to 50 years, P <0.05. It can be that H. pylori participate with high rate in GITDs patients particularly IBD elderly patients.