Novel Substituted Indazoles towards Potential Antimicrobial Agents-Reference-Cited by-同舟云学术

Novel Substituted Indazoles towards Potential Antimicrobial Agents

Published:2021-04-30 Issue:2 Volume:37 Page:508-512
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

Saketi Jaganmohana Rao¹^ORCID,Boddapati S N Murthy²^ORCID,M Raghuram³^ORCID,Koduru Geetha Bhavani⁴^ORCID,Bollikolla Haribabu¹^ORCID

Affiliation:

1. Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, A. P.,India.

2. Department of Chemistry, Sir C R Reddy College, P G Courses, Eluru, A.P-534007, India.

3. Department of Botany and Microbiology, Acharya Nagarjuna University,Guntur-522510, A.P., India.

4. Department of Chemistry, J. M. J. College for Women, Tenali, Guntur Dist, A.P., India.

Abstract

The in vitroantimicrobial properties of a series of N-methyl-3-aryl indazoles (5a-5j) were screened. In this present work, we describe our efforts towards the development of potent antimicrobial activity of synthesized indazole derivatives. The antimicrobial activities of the prepared compounds were investigated against four bacterial strains: Xanthomonas campestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and a fungal strain Candida albicans. The biological evaluation studies of these indazole derivatives revealed that some of these tested compounds have shown moderate to goodin vitroantimicrobial activities.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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