Age of Laboratory Hamster and Human: Drawing the Connexion

Author:

Dutta Sulagna1,Sengupta Pallav2

Affiliation:

1. Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, MAHSA University, Malaysia.

2. Department of Physiology, Faculty of Medicine, MAHSA University, Malaysia.

Abstract

Hamsters have unique physiological characteristics rendering them well-suited for biomedical research as experimental model. They match beneficial traits of both smaller rodents and larger mammals that make them suitable for laboratory use, such as availability, breeding ease, greater tissue proportions and the like. In experimental design, it is inevitable to select laboratory animals of accurate age that can mimic the target human age in a specific research. In this article, we have calculated that one human year equals 13.67 hamster days, considering their entire lifespan. This simplistic calculation may not find universal relevance in biomedical research, given the accelerated non-uniform life stages of hamsters when matched with human. To resolve this issue, this is the first ever article where we have provided a concise perception of hamster days in human years by correlating their age at every major life stage. This article will aid precision in biomedical research via selection of laboratory hamster of accurate age corresponding to human age, which is the most primary and essential criteria in animal based research.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

Reference68 articles.

1. Bartlett P. P. The hamster handbook, in: Bartlett P. (Ed.), Barron’s Educational Series 2nd ed. Barron’s Educational Series. 2015.

2. Blaha G. C. Reproductive senescence in the female golden hamster. The Anatomical Record. 1964;150:405-411.

3. CrossRef

4. Calado A. M., dos Pires M. A. An Overview of Teratology, in: Felix, L. (Ed.), Teratogenicity Testing 1st ed. Springer. 2018;XV:614.

5. CrossRef

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