Renal Outcome and Health Related Quality of Life of Living Related Donors In Pediatric Kidney Transplantation

Author:

G. Fathallah Mohamed1ORCID,I. Fadel Fatina1ORCID,Eldin Saadi Gamal2ORCID,Abdel Mawla Mohamed A.3ORCID,M. Salah Doaa1ORCID

Affiliation:

1. 1Department of Pediatrics, Cairo University, Cairo, Egypt

2. 3Department of Internal Medicine, Cairo University, Cairo, Egypt

3. 2Departmentof Pediatrics, National Research Center, Giza, Egypt

Abstract

Objectives To assess the health related quality of life of living related donors after kidney transplantation and to evaluate clinical ,social and psychological condition post donation Study design This is an observational cross sectional study that included fifty living related donors of kidney transplant. All donors were assessed after at least one year of kidney donation. Data of the study was collected between April, 2019 and March, 2020. Methods The study included 50 living related donors;All donors were assessed after at least one year of kidney donation.WHOQOL-bref questionnaire (world health organization quality of life ) was used to assess quality of life of donors. Results The mean age at time of transplantation was 35.4±7.89 years. Eight cases developed hypertension after transplantation. There was no significant difference between serum creatinine before and after transplantation while there was significant decrease in glomerular filtration rate post transplantation. There was significant increase in fasting blood glucose and cholesterol in female donors compared to males.The results of the WHOQOL-bref questionnaire showed significant difference in results of psychological, social and environmental domains pre and post donation. Conclusion Proper selection of donors is very important to avoid complications post transplantation. Follow-up of donors should be maintained after donation.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

Reference41 articles.

1. de Fijter JW, Meinders A. [Long live the kidney donor] Lang leve de nierdonor. Ned TijdschrGeneeskd 2014; 158: A8180.

2. Cecka JM. The UNOS Scientific Renal Transplant Clin Transplant 2000:1e18.

3. Abecassis M, Adams M, Adams P, et al. Consensus statement on the live organ donor. JAMA 2000;284:2919.

4. CrossRef

5. Steiner R, Matas AJ. First things first: laying the ethical and factual groundwork for living kidney donor selection standards. Am J Transplant 2008;8:930.

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