Tetracyclines: The Old, the New and the Improved - A Short Review

Abstract

The most frequently prescribed antibiotic class in dermatology is the tetracycline family, which has both antibacterial and anti-inflammatory characteristics. Tetracycline is a broad-spectrum polyketide antibiotic effective against gram-positive and gram-negative organisms. It has been accepted for the therapeutic use of various conditions in dermatology like Acne, Rosacea, Syphilis, Immuno-bullous dermatoses, Pyoderma gangrenosum and Hidradenitis Suppurativa to name a few. However, the use and efficacy of newly discovered tetracyclines like Sarecycline, Omadacycline and Tigecycline are still yet to be documented and researched. In this study, a short summary of the utilization of various tetracycline are being documented for their use in dermatology.