Histological Investigation of the Hepatic Tissue in Mice Induced by Soft Laser with Different Doses

Author:

Albir Ahmed Anwar1,Al- Kaisy Aedah Z.2

Affiliation:

1. Department of Basic Sciences, College of Dentistry, University of Baghdad, Iraq.

2. Department of Physiology, College of Medicine, University of Baghdad, Iraq.

Abstract

Our experimental study was conducted on twenty seven healthy male albino mice, whose ages ranged from 5 to 6 weeks and weight range was 23-26gm with standard deviation (Std) equals to 1.83. The mice were randomly divided into three groups (9 mice each). The first group of mice was served as a control and not irradiated with laser, while both second and third groups of mice were anaesthetized and irradiated by using diode laser (λ = 890nm) which was focused on the upper right quadrant of the abdomen where the liver is located. It was concluded from our study that although laser exposed to both second and third groups of mice for 5 and10 minutes once daily respectively during the entire period of experimentation (6 days), the laser did not affected their hepatic tissue structure.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

Reference17 articles.

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2. Ramadori, G., Moriconi, F., Malik, I. & Dudas, J. (2008), “Physiology and Pathophysiology of Liver Inflammation, Damage and Repair”, Journal of Physiology and Pharmacology 59, Suppl 1,107-117.

3. Grisham, J.W., Nopanitaya, W., Compagno, J. & Nägel, A.E. (1975), “Scanning electron microscopy of normal rat liver: the surface structure of its cells and tissue components”, Am J Anat 144, 295-321.

4. Haubrich, W. S. (2004), “Kupffer of Kupffer cells”, Gastroenterology 127, 16.

5. Tu, C-T., Yao, Q-Y., Xu, B-L & Zhang, S-C. (2013), “Curcumin protects against concanavalin A-induced hepatitis in mice through inhibiting the cytoplasmic translocation and expression of high mobility group box1”, Inflammation 36 (1), 206-215.

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