Author:
Zeenath Anwar Parvin,Gowrie Sezhian Uma,Narasingam Arunagirinathan
Abstract
ABSTRACT: The medicinal plant Cissus quadrangularis has been extensively explored with respect to the presence of phytochemicals and their bioactivities. The available research data on endophytic bacteria of this plant is very limited. The main objective of this study is to isolate endophytic bacteria from the stem of Cissus quadrangularis and to determine the presence of bioactive compounds, antioxidant and antiosteosarcoma potential of the extracellular ethyl acetate crude extracts of endophytic bacteria. One of the isolates CqB14 was identified to be similar to Pseudomonas sp. as analyzed by 16S rRNA sequencing. Qualitative phytochemical screening and HPTLC analysis of the extracellular ethyl acetate crude extract of CqB14 showed the presence of alkaloids in addition to other secondary metabolites. GCMS analysis predicted the presence of antimicrobial and anticancerous compounds. This study also reveals the antioxidant and antiosteosarcoma potential of endophytic bacteria from Cissus quadrangularis.
Publisher
Oriental Scientific Publishing Company
Subject
Drug Discovery,Agronomy and Crop Science,Biotechnology
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