Microwave Assisted Synthesis Of Novel 2-Pyrazolines From Furan Based Chalcones and Study their Antimicrobial Actvity-Reference-Cited by-同舟云学术

Microwave Assisted Synthesis Of Novel 2-Pyrazolines From Furan Based Chalcones and Study their Antimicrobial Actvity

Published:2022-10-31 Issue:5 Volume:38 Page:1306-1310
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

Kumbhare Santosh Laxman¹,Meshram Yuvraj Khushal²

Affiliation:

1. https://www.orientjchem.org/vol38no5/microwave-assisted-synthesis-of-novel-2-pyrazolines-from-furan-based-chalcones-and-study-their-antimicrobial-activity/

2. 2Department of Chemistry, G.S. College, Khamgaon, Dist.- Buldana (M.S.),444303, India

Abstract

Nitrogen heterocyclic compounds such as2-pyrazoline showing various pharmacological activities such as antibacterial, antifungal, antioxidant, antidepressant, anti-inflammatory, anticancer, and antitubercular activities. This promotes to synthesize 2-pyrazolines by the reaction of different substituted chalcones of 2-Acetyl Furan and hydrazinehydrate in the presence alcohol. Synthesized compound was confirmed by physical data such as melting point and various spectral analysis such as FTIR, NMR spectra. Antimicrobial activity of synthesized compound was evaluated. The results indicated that some of compounds show good antibacterial and antifungal activity.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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