Catalyst-Free Multicomponent Synthesis of Novel Chromene Carbonitriles from Pyrazole Aldehydes using Ethanol-Reference-Cited by-同舟云学术

Catalyst-Free Multicomponent Synthesis of Novel Chromene Carbonitriles from Pyrazole Aldehydes using Ethanol

Published:2022-10-31 Issue:5 Volume:38 Page:1156-1164
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

Jayanthi Selvaraj¹^ORCID,Sugumaran Thangarajan²,Monisha Periyasamy¹^ORCID,Gunasundar Kittappa¹^ORCID,Vetriselvan Moorthy¹^ORCID,Pramesh Manickam¹^ORCID,Venkatachalam Ragunathan¹

Affiliation:

1. 1Department of Chemistry, A.V.V.M. Sri Pushpam College, (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi-613503, Tamil Nadu, India.

2. 2Department of Chemistry, Ayya Nadar Janaki Ammal College, Sivakasi (Affiliated to Madurai University), Madurai, Tamil Nadu, India

Abstract

A catalyst-free synthetic strategy to chromene carbonitriles by Multi-Component Reaction of pyrazole aldehydes, 5,5-dimethylcyclohexane-1,3-dione and malononitrile with ethanol, at room temperature is reported. Screening of solvents and purification of the compounds were also performed. The newly synthesized novel compound’s (4H-chromene-3-carbonitriles) structures were authenticated by the spectral techniques viz. (1H , 13C)Nuclear Magnetic Resonance, FT-IR, and LC-MS analysis.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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