Kinetics and Mechanisms of Ligand-Exchange of Cu(Methionine)2 by Polyamines-Reference-Cited by-同舟云学术

Kinetics and Mechanisms of Ligand-Exchange of Cu(Methionine)2 by Polyamines

Published:2022-12-30 Issue:6 Volume:38 Page:1567-1570
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

Moheman Abdul¹^ORCID,Bhawani Showkat Ahmad²^ORCID,Siddiqi Khwaja Salahuddin³^ORCID

Affiliation:

1. 1Department of Chemistry, Gandhi Faiz-E-Aam College, Shahjahanpur (Affiliated to M J P Rohilkhand University, Bareilly), Uttar Pradesh, India.

2. 2Faculty of Resource Science and Technology, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.

3. 3Department of Chemistry, Aligarh Muslim University, Aligarh-202002, UP, India.

Abstract

The kinetics of ligand substitution reaction of Cu(methionine)2 complex by polyamines has been followed conductometrically above pH 9.0 at 25 oC. Millimolar solution of the Cu(NO3)2 and methionine in 1:2 molar ratio in water shows increase in conductance with time. When a polyamine (en, dien and trien) is added to the complex, the conductance increases at a rapid rate due to substitution of methionine by polyamine leading to the formation of [Cu(polyamine)2]. It was observed that the exchange of methionine by polyamine proceeds in a first order process. Since the rate of the reaction varies with the size of polyamines they can be placed in the following, en > dien > trien. In acidic pH range the absorption spectrum varies negligibly. However, the concentration of methionine does not have any influence on the absorption spectra.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

Reference19 articles.

1. 1. Laurie S. H. “Comprehensive coordination chemistry”, ed. G. Wilkinson G., R.D. Gillard R. D.; McCleverty J. A., Vol. 2, Pergamon Press, Oxford, 1987, pp 739-776.

2. 2. Festa R. A.; Thiele D. J., Current Biology, 2011, 21, R877-83.

3. 3. McAuliffe C. A.; Quagliano J. V.; Vallarino L. M., Inorganic Chemistry., 1966, 5, 1996-2003.

4. 4. Kiss T.,“Biocoordination Chemistry: Coordination equilibria in biologically active systems” ed. K. Burger, Ellis Horwood, Chichester, pp 56–134, 1990.

5. 5. Laurie S. H., “Handbook of metal–ligand interactions in biological fluids: bioinorganic chemistry”, ed. G. Berthon, Vol. 1, Marcel Dekker, New York, pp 603–619, 1995.