Synthesis and Characterization of ZnO@SiO2 Nanocomposite using Gum Arabic and its Larvicidal Activity on Malaria Vectors

Author:

Shehu Zaccheus1ORCID,Abba Ezra2ORCID,Abubakar Zainab Adamu3ORCID,Dogara Rifkatu Kambel4ORCID,Ayuk Nsor Charles2ORCID

Affiliation:

1. 1Department of Chemistry, College of Natural Science, Makerere University, Kampala, Uganda.

2. 2Department of Zoology, Faculty of Science, Gombe State University, Gombe PMB 127, Nigeria.

3. 3Department of Biological Sciences, Faculty of Science, Gombe State University, Gombe PMB 127, Nigeria.

4. 4Department of Chemistry, Faculty of Science, Gombe State University, Gombe PMB 127, Nigeria.

Abstract

Green synthesis of ZnO@SiO2 nanocomposite was performed using Gum Arabic. The green synthesized nanocomposite was characterized using Fourier Transform Infrared Spectrophotometer (FTIR), The Scanning Electron Microscopy (SEM), UV-Visible spectrophotometer, Dynamic Light Scattering (DLS), and X-Ray Fluorescence (XRF). The toxicity study was conducted for 24 hours on 1st to 4th larval instars of malaria vectors at various concentrations (10, 20 and 25 mg/L). The LC50 and LC90 for the 1st - 4th larval instars were found to be in the range of 9.11 - 18.288 mg/L and 157.254 - 126.132 mg/L respectively. A strong positive correlation between concentrations of the nanocomposite and mortality of larval instars (0.945 - 0.997). These values indicate that the mortality rates increased with an increase in concentrations. ZnO@SiO2 nanocomposite is a potential nano-larvicide for malaria vector control in tropical countries with high malaria incidence.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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