Study of Zn(II)- Salicylidene–4-(p–chlorophenyl)–2–Aminothiazole Complex by Polarographic Method with its Antibacterial Activity
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Published:2022-10-31
Issue:5
Volume:38
Page:1255-1260
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ISSN:2231-5039
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Container-title:Oriental Journal Of Chemistry
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language:en
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Short-container-title:Orient. J. Chem
Author:
Solanki Manohar1ORCID, Gautam Mangla Dave2ORCID, R. Chourey Vijay3ORCID
Affiliation:
1. 1Department of Chemistry Government. College, Thandla-457777 (M.P.) India 2. 2Department of Chemistry, Mata Jija-Bai Govt. Girls College, Indore-452009 (M.P.) India. 3. 3Department of Chemistry, Government. Holkar Science College, Indore- 452017 (M.P.) India
Abstract
Newly Zn(II)-salicylidene–4–(p-chlorophenyl)–2–aminothiazole (SCAT) ligand was synthesized and studied in DMF media by the polarographic method and produce a DC and DPP polarogram in KCl (supporting electrolyte) with Britton- Robinson buffer. The far FT- IR spectral study show signals at 465 and 412 cm−1 respectively which confirm the metal-ligand bonding. The serial tube dilution method (MIC) was used for investigating the antibacterial activity of this newly synthesized complex and ligand toward pathogenic bacteria, B. subtilis, and E. coli. The results concluded that the ligand enhanced the biological activity when it binds with Zn(II) ion.
Publisher
Oriental Scientific Publishing Company
Subject
Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry
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