Renoprotective Effects of Anthocyanins Against Uric AcidInstigated Injury: Mini Review with a Special Emphasis on Purple Sweet Potato (Ipomoea batatas L.) Anthocyanins

Author:

Mahendra Agung Nova1ORCID,Jawi I Made2ORCID,Astawa Nyoman Mantik3ORCID,Astawa Putu4ORCID,Sutirta-Yasa I Wayan Putu5ORCID

Affiliation:

1. 2Doctoral Study Program in Biomedical Science, Faculty of Medicine, Universitas Udayana, Denpasar, Bali, Indonesia.

2. 1Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Udayana, Denpasar, Bali, Indonesia.

3. 3Virology Laboratory, Faculty of Veterinary Medicine, Universitas Udayana, Denpasar, Bali, Indonesia.

4. 4Department of Orthopedics and Traumatology, Faculty of Medicine, Universitas Udayana and RSUP Prof I G. N. G. Ngoerah, Denpasar, Bali, Indonesia.

5. 5Department of Clinical Pathology, Faculty of Medicine, Universitas Udayana and RSUP Prof I G. N. G. Ngoerah, Denpasar, Bali, Indonesia.

Abstract

Anthocyanins are ubiquitous phytoconstituents found in a wide array of natural products. Purple sweet potato (Ipomoea batatas L.) is an important source of anthocyanins, a group of flavonoids with various medicinal benefits. One of the medicinal benefits of anthocyanins is their protection against the detrimental effects of stressors such as uric acid. On the other hand, hyperuricemia and its associated effects are considered significant challenges in human health. Since kidneys are essential organs in uric acid handling and uric acid is associated with kidney disease, this review focuses on re-appraising the role of purple sweet potato anthocyanins as renoprotectors against uric acid-related pathobiology. Future studies regarding the potential of these anthocyanins as renoprotectors are also discussed.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

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