Comprehensive Review on COVID-19 associated Mucormycosis: Diagnosis, Types and Treatment

Abstract

ABSTRACT: In the past couple of years, the world has been dealing with a dreadful pandemic known as Covid-19 along with one of the life-threatening infection i.e. mucormycosis. Mucormycosis (Zygomycosis) is a fungal infection caused by a group of molds called mucormycosis. Several clinical cases of mucormycosis have been reported globally during the Covid-19 pandemic. Patients with compromised immunity or uncontrolled diabetics or patients that were given steroid therapy to combat infection due to corona virus were at high risk of acquiring mucormycosis as co-morbidity associated with Covid-19. In the present review, various types of mucormycosis, diagnosis, and treatment strategies are explained as it is associated with high morbidity and mortality. Amphotericin B liposomal formulation was found to be the most widely used to treat mucormycosis. Other antifungal agents and adjuvant therapies were also tried to treat this infection.