To Check the Efficacy of American Academy of Paediatrics (AAP) Recommended Dose of Vitamin D in Healthy Breastfed Newborns

Abstract

ABSTRACT: Background: Vitamin D supplements are necessary for breastfed newborns, although little is known regarding the effectiveness of AAP’s recommended dose of 400 IU per day of it. This randomized controlled trial evaluates the efficacy of above-mentioned dose. Method: Exclusively breastfed newborns (N=28) were block randomized in two groups, vitamin D supplemented (VitD-S) and without supplement (VitD-U), 400IU/day of vitamin D is provided to Vit D-S. Serum vitamin D was assessed at the enrolment and at 3 months. Results: Vitamin D level compared between two groups, in Vit D-S at birth it was 20.4±8.7ng/ml and at 3 months it rises to 24.8±6.1ng/ml while in Vit D-U fall in level is seen from 21.4±7.8ng/ml to 14.0±5.1ng/ml which is statistically significant (p<0.001). Conclusion: Vitamin D is deficiency is quite common among mothers and babies in this location, and supplementing with 400 IU of vitamin D per day increased 25(OH)D levels in the plasma.