Antimicrobial Activity of Calix[4]pyrrole-entrenched Silver Nanoparticles and Its Application as Colorimetric and Spectrophotometric Sensing of L-Histidine

Author:

C. Pomal Nandan1ORCID,Bhatt Keyur D.1ORCID,Kundariya Dinesh S.2ORCID

Affiliation:

1. 1Department of Chemistry, Faculty of Science, Ganpat University, Mehsana, Gujarat, India.

2. 2Department of Chemistry, Tolani College of Arts and Science, KSKV Kutch University, Bhuj, Gujarat, India

Abstract

A calix[4]pyrrole tetrahydrazide functionalized silver nanoparticles (CPTPH-AgNPs) coupled with colorimetric findings were prepared. In the variety of essential amino acids, it detected the L-Histidine exclusively with an LOD of 6.1 μM and LOQ of 18.5 μM. The CPTPH-AgNPs were exhibited the SPR spectrum at 408nm, which further characterized with TEM, EDEX and SAED in that they show the monodispersed spherical morphology of AgNPs with 13±2nm size. The antimicrobial potential of CPTPH-AgNPs towards Gram-positive bacterial-Staphylococcus aureus, Bacillus subtilis, Gram-negative bacteria-Escherichia coli, Pseudomonas aeruginosa and fungi-Aspergillus niger was evaluated.; in which it is found to give reasonable response comparable to standard antibiotic drugs.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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