Anti-Oxidant Activities, Dosage of Total Polyphenols and Flavonoids from Crossopteryx febrifuga (AFZ. Ex G. Don) Benth (Rubiaceae)-Reference-Cited by-同舟云学术

Anti-Oxidant Activities, Dosage of Total Polyphenols and Flavonoids from Crossopteryx febrifuga (AFZ. Ex G. Don) Benth (Rubiaceae)

Published:2022-12-27 Issue:6 Volume:39 Page:1620-1628
ISSN:2231-5039
Container-title:Oriental Journal Of Chemistry
language:en
Short-container-title:Orient. J. Chem

Author:

Séverin Mbaïhougadobé¹^ORCID,Salomon Madjitoloum Bétoloum²^ORCID,Cudalbeanu Mihaela³^ORCID,Abel Mbaïogaou²,Furdui Bianca³^ORCID,Dinică Rodica Mihaela³

Affiliation:

1. 1Université de Moundou, BP : 206 Moundou/Tchad.

2. 2Research Laboratory of Natural Substances, FSEA of University of N’Djaména, Chad.

3. 3Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, Dunarea de Jos University of Galati, Romania.

Abstract

The aim of this study was to determine the total polyphenols and flavonoids in extracts of Crossopteryx febrifuga (AFZ. Ex G. Don) Benth (CF) and to evaluate their antioxidant activity. TLC also reveals the presence of free phenolic acids, flavonoids. Determination of these compound families in the extracts yielded high levels of polyphenols and flavonoids in ethyl acetate extracts, with polyphenols at 264.233 mg and flavonoids at 111.784 mg. the qualitative method for determining antioxidant activity using the DPPH TLC method, gives yellow streaks indicating activity. The ethyl acetate extract showed greater inhibition than the other two extracts with the two radicals used. The extracts inhibited the DPPH radical at 35 min and ABST at 120 min. The results obtained would justify the use of this plant species in traditional medicine in Chad.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

Reference22 articles.

1. 1. Talla, E., Ngenge Tamfu, A., Gade, I., Yanda, L., Tanyi Mbafor, J., Laurent, S., & Vander Elst, L. (2017). New mono-ether of glycerol and triterpenes with DPPH radical scavenging activity from Cameroonian propolis. Natural Product Research, 31(12), pp. 1379-1389.

2. 2. Bruneton J. (2009). Pharmacognosie, Phytochimie, Plantes médicinales. 4ème Ed revue et augmentée. Editions médicales internationales, éditions Tec & Doc Lavoisier. Paris. 1269 P.

3. 3. Halliwell, B., Cross-, C. E. (1994). Oxygen-derived species: their relation to human disease and environmental stress.

4. 4. Bealem Aristide, Sakava Paul, Lidia Favier, Didier Hauchard, Jean-Paul Guegan, Nyemb Jean Noël , . . . Mbafor Tanyi Joseph. (2021). Chemical Constituents of Crossopteryx febrifuga (Afzel ex G. Don) Benth (Rubiaceae), their Phytotoxicity and Antioxidant Activities. Natural products chemistry and research, 9(1000416).

5. 5. MBAIHOUGADOBE Séverin. (2017). Phytochimie et pharmacologie des plantes utilisées dans le traitement de la goutte au Tchad. Thèse de Doctorat, Université Marien Ngouabi.173 P.